Deducing the right model for DNA replication
The 3 hypothesized models of DNA replication
The experimental evidence
Guiding questions
Discuss within your group by posting your individual comments and hence showing how you derive at the answer for the following questions. Publish your group's final conclusion/answer for each question.
1.) What would be the expected observations if the experiment shown were performed for each of the model (a), (b) and (c). (Your group's answer should have expected experimental observations for model (a), (b) and (c))
1.) What would be the expected observations if the experiment shown were performed for each of the model (a), (b) and (c). (Your group's answer should have expected experimental observations for model (a), (b) and (c))
2.) What is the use of allowing the cells to carry out a second replication? Can we determine the correct model if the cells were only allowed one replication?
3.) Which hypothesized model (a), (b) or (c) followed the experimental evidence as shown? Therefore, what is the model for DNA replication?
Teacher's copy:
1.) Expected observation
2.) Both the dispersive and semiconservative model showed the same experimental result after first replication. The experimental results from the second replication eliminated the dispersive model as it was not consistent with the actual experimental result obtained. Therefore, the second replication allowed scientists to eliminate the wrong model (dispersive) and confirm the correct model (semiconservative).
3.) Model (b), semiconservative model followed the experimental evidence as shown. The correct model for DNA replication is semiconservative model.
